Xanthogranulomatous Cholecystitis Mimicking Biliary Tract Cancer
نویسندگان
چکیده
We present a 42-year-old man with a 1-month history of painless jaundice, dark urine, clay-colored stools, and a 13.5-kg weight loss. Laboratory tests revealed elevated liver enzymes and CA19-9. Imaging showed dilation of both the intra- and extrahepatic bile ducts, narrowing of the bile duct at the junction of the common bile duct and common hepatic duct, and a hypoechoic mass involving the neck of the gallbladder and the muscularis propria of the duodenum. Examination of the resected gallbladder and perihilar nodes ruled out malignancy and revealed a diffuse inflammatory infiltrate of giant histiocytes with clear, lipid-containing cytoplasm (xanthoma cells), consistent with xanthogranulomatous cholecystitis.
منابع مشابه
Infiltrative xanthogranulomatous cholecystitis mimicking aggressive gallbladder carcinoma: A diagnostic and therapeutic dilemma
Xanthogranulomatous cholecystitis (XGC) is an uncommon variant of chronic cholecystitis. The perioperative findings in aggressive cases may be indistinguishable from those of gallbladder or biliary tract carcinomas. Three patients presented mass lesions that infiltrated the hepatic hilum, provoked biliary dilatation and jaundice, and were indicative of malignancy. Surgical excision was performe...
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Xanthogranulomatous cholecystitis (XGC), a rare form of chronic cholecystitis which fairly mimics gallbladder cancer, was first discovered and reported by McCoy et al. [1]. Although it is considered as benign disease but often reported its close association with gallbladder cancer (GBC) [2,3]. Clinical signs and symptoms are similar to acute and chronic cholecystitis, thus preoperative diagnosi...
متن کاملXanthogranulomatous Cholecystitis Presenting as Empyema Gallbladder in Patient of Chronic Cholecystitis with Cholelithiasis
Xanthogranulomatous cholecystitis (XGC), a rare form of chronic cholecystitis which fairly mimics gallbladder cancer, was first discovered and reported by McCoy et al. [1]. Although it is considered as benign disease but often reported its close association with gallbladder cancer (GBC) [2,3]. Clinical signs and symptoms are similar to acute and chronic cholecystitis, thus preoperative diagnosi...
متن کاملXanthogranulomatous cholecystitis: a clinicopathological study from a tertiary care health institution.
BACKGROUND Xanthogranulomatous cholecystitis is an unusual and destructive form of chronic cholecystitis and is indistinguishable from other forms of cholecystitis which makes preoperative diagnosis and surgery difficult. OBJECTIVES To review the demographic and clinical aspects of xanthogranulomatous cholecystitis; to study the possibility of preoperative diagnosis and to identify the causes...
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Purpose: Xanthogranulomatous cholecystitis (XGC) is an uncommon, benign destructive and chronic inflammatory disease which is characterized by a marked proliferative fibrosis within the gallbladder wall. XGC occasionally involves adjacent organs and mimicking an advanced gallbladder carcinoma (GBC). The purpose of this study was to review the clinical manifestations, radiologic and pathologic f...
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